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92567ESRecombinant Human Thymosin beta 4/Tβ-4 Protein
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訪問次數(shù):237更新時間:2025-03-19 08:55:26

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初級會員·13年
聯(lián)人:
曹女士
話:
400-6111-883
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4006-111-883
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86-21-34615995
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產(chǎn)品簡介
供貨周期 兩周 應(yīng)用領(lǐng)域 醫(yī)療衛(wèi)生,生物產(chǎn)業(yè)
Thymosin Beta 4 is a naturally occurring peptide encoded by the TMSB4X gene located on Chr. X in humans. It is found in high concentrations in blood platelets, wound fluid and other tissues in the bod
產(chǎn)品介紹

Product Description

 

Thymosin Beta 4 is a naturally occurring peptide encoded by the TMSB4X gene located on Chr. X in humans. It is found in high concentrations in blood platelets, wound fluid and other tissues in the body. Tβ-4 is a major actin regulating peptide and the primary function is to stimulate the productions of T cells, which plays important part of the immune system. The thymosin beta-4 peptide, if used after a heart attack, might reactivate cardiac progenitor cells to repair damaged heart tissue.

 

Product Properties

 

Synonyms

Fx

Accession

P62328

GeneID

7114

Source

E.coli-derived human Tβ-4 protein, Ser2-Ser44.

Molecular Weight

Approximately 4.9 kDa.

AA Sequence

SDKPDMAEIE KFDKSKLKKT ETQEKNPLPS KETIEQEKQA GES

Tag

None

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

The biological activity determined by its ability to produce a protective effect against hydrogen peroxide in primary lung fibroblasts is in a concentration range of 0.5 - 10 μg/mL. Fully biologically active when compared to standard.

Endotoxin

< 1.0 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20. Further dilutions should be made in appropriate buffered solutions.

 

Shipping and Storage

 

The products should be stored at -25 to -15℃ for 1 year.  

1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

 

  1. Avoid repeated freeze-thaw cycles.

  2. For your safety and health, please wear lab coats and disposable gloves for operation.

  3. For research use only!

 




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