目錄:杭州斯達(dá)特生物科技有限公司>>抗體/抗原>>標(biāo)簽/內(nèi)參抗體>> S0B1820Lamin A/C Recombinant Rabbit mAb (HRP Conjugate) (SDT-R041)
參考價(jià) | ¥ 480 |
參考價(jià) | ¥ 480 |
更新時(shí)間:2025-06-04 11:54:32瀏覽次數(shù):20評(píng)價(jià)
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Lamin A/C is a crucial nuclear protein encoded by the LMNA gene, playing a significant role in maintaining the structural integrity of the cell nucleus. It is part of the nuclear lamina, a fibrous layer that provides support to the nuclear envelope and helps in organizing the chromatin. Beyond its structural function, lamin A/C is involved in various cellular processes, including gene regulation, DNA replication and repair, cell differentiation, and mechanosensing. Mutations in the lamin A/C gene can lead to a range of diseases collectively known as laminopathies, which include muscular dystrophy, lipodystrophy, and certain forms of cardiomyopathy. Additionally, lamin A/C has been implicated in cancer, where its deregulation can contribute to genomic instability and affect the mechanical resilience of tumor cells.
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