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APC (phospho Ser2054) rabbit pAb
  • APC (phospho Ser2054) rabbit pAb
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更新時(shí)間:2025-03-10 21:00:08

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SourceRabbitApplicationsWB,IHC,ELISAReactivityHumanDilutionWB:1:500-1:2000
  • Source

    Rabbit

  • Applications

    WB,IHC,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-APC (S2054) Polyclonal Antibody detects endogenous levels of APC protein only when phosphorylated at S2054.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human APC around the phosphorylation site of Ser2054. AA range:2020-2069

  • Uniprot No

    P25054

  • Alternative names

    APC; DP2.5; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    APC, WNT signaling pathway regulator(APC) Homo sapiens This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008],

  • Other

    APC, Adenomatous polyposis coli protein

  • Mol.Wt (Da)

    311646

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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