QQ交談
您所在位置：請輸入產品關鍵字：
郵編：100083
聯(lián)系人：尤女士
電話：4008858216
傳真：
手機：13581534696
留言：發(fā)送留言
個性化：www.qbiotec.com
網址：www.qbiotec.com
商鋪：http://www.hbwxwy.cn/st289923/
【產品簡介】
【詳細說明】
GsMTx4
Selective blocker of mechanosensitive ion channels
壓力敏感性離子通道選擇性阻斷劑
GsMTx4 (GsMTx-4, M-theraphotoxin-Gr1a) has been isolated from the venom of the spider Grammostola rosea. This cationic hydrophobic polypeptide blocks selectively the gating of cation selective channels and mechanosensitive ion channels such as TRPC1 or TRPC6, without having any effect on whole-cell voltage-sensitive currents. This toxin acts by perturbing the interface between the channel and the lipid bilayer without necessarily being in physical contact with the channel. GsMTx4 also demonstrated to active TRPA1 channel at 1µM concentration and to inhibit Piezo1 currents.
GsMTx4 技術資料
氨基酸序列：
Gly-Cys2-Leu-Glu-Phe-Trp-Trp-Lys-Cys9-Asn-Pro-Asn-Asp-Asp-Lys-Cys16-Cys17-Arg-Pro-Lys-Leu-Lys-Cys23-Ser-Lys-Leu-Phe-Lys-Leu-Cys30-Asn-Phe-Ser-Phe-NH2
二硫鍵：Cys2-Cys17, Cys9-Cys23 and Cys16-Cys30
長度 (aa)：34
分子式：C185H273N49O45S6
分子量：4095.2 Da
外觀：White lyophilized solid
可溶性：water and saline buffer
CAS 號：not available
來源： Synthetic
純度： > 97 %
產品信息
08GSM001-00050 | GsMTx4 | 0.05mg |
08GSM001-00100 | GsMTx4 | 0.1mg |
08GSM001-00500 | GsMTx4 | 0.5mg |