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南京科佰生物科技有限公司
主營(yíng)產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫(kù)購(gòu)買(mǎi) |
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南京科佰生物科技有限公司
主營(yíng)產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫(kù)購(gòu)買(mǎi) |
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| 參考價(jià) | 面議 |
更新時(shí)間：2022-09-16 11:51:51瀏覽次數(shù)：768
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| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 1ug |
|---|---|---|---|
| 貨號(hào) | CBP10293 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
CBP10293 | |
| Format | Genomic DNA |
| Description | KRAS G12V is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). G12V results in decreased Kras GTPase activity and increased activation of downstream signaling in cell culture, and leads to increased tumor growth in mouse models (PMID: 23455880, PMID: 26037647, PMID: 24642870) and is transforming in cell culture (PMID: 29533785). |
| Technical Data | |
| DNA Change | c.35G>T |
| AA Change | p.G12V |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000311936 |
| Cosmic ID | COSM520 |
| Chr position(GRCh37) | chr12:25398284 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
